The Milwaukee Bucks will play without their two best players in Game 4 against the Indiana Pacers on Sunday while facing a 2-1 series deficit.

The Bucks announced early Sunday that Damian Lillard and Giannis Antetokounmpo will both be sidelined for the critical game.

Antetokounmpo will miss a sixth straight game with a calf strain that's sidelined him since April 10. Lillard aggravated an Achilles injury late in Game 3 Friday night and was seen wearing a walking boot on Saturday. Head coach Doc Rivers told reporters Saturday that the team was awaiting the results of an MRI prior to Lillard being ruled out Sunday.

Damian Lillard and Giannis Antetokounmpo will both miss Game 4 against the Pacers. (Ethan Miller/Getty Images)

The injuries leave the Bucks at a significant disadvantage, two days after losing a 121-118 Game 3 overtime thriller that gave the Pacers the 2-1 series advantage. Lillard was injured late in regulation, then failed to score in overtime while playing through the injury. Pacers All-Star Tyrese Haliburton hit the game-winning bucket on an and-1 floater with 1.1 seconds remaining in overtime.

The Bucks will look for increased production from Khris Middleton, Bobby Portis and Brook Lopez in the absence of their two All-Stars.

Lillard averaged 24.3 points and seven assists in the regular season and stepped up his production in the playoffs with Antetokounmpo sidelined. In Games 1-3, Lillard averaged 32.3 points, 5.3 assists and 3.7 rebounds while shooting 44.4% on 12 3-point attempts per game.

Milwaukee has struggled this season without Lillard on the floor. They went 1-8 in the regular season in games he didn't play. It's not clear when Lillard or Antetokounmpo will be able to return to the floor.